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1

2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV) (Part 1 – small molecules, peptides and small molecule biomarkers by LCMS)

Yang, Eric, Welink, Jan, Cape, Stephanie, Woolf, Eric, Sydor, Jens, James, Christopher, Goykhman, Dina, Arnold, Mark, Addock, Neil, Bauer, Ronald, Buonarati, Michael, Ciccimaro, Eugene, Dodda, Raj, Ev

Journal:

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

2

Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC–MS

Mehl, John T, Sleczka, Bogdan G, Ciccimaro, Eugene F, Kozhich, Alexander T, Gilbertson, Deb G, Vuppugalla, Ragini, Huang, Christine S, Stevens, Brenda, Mo, Jingjie, Deyanova, Ekaterina G, Wang, Yun, H

Journal:

Year:

2016

Language:

english

File:

PDF, 6.92 MB

english, 2016

3

The balance between pro-apoptotic and anti-apoptotic pathways in the failing myocardium

Brian S. McGowan, Eugene F. Ciccimaro, Tung O. Chan, Arthur M. Feldman

Journal:

Cardiovascular Toxicology

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

4

Differential mobility spectrometry combined with multiple ion monitoring for bioanalysis of disulfide-bonded peptides with inefficient collision-induced dissociation fragmentation

Xia, Yuan-Qing, Ciccimaro, Eugene, Zheng, Naiyu, Zhu, Mingshe

Journal:

Year:

2017

Language:

english

File:

PDF, 1.26 MB

english, 2017

5

A peptide immunoaffinity LCâMS/MS strategy for quantifying the GPCR protein, S1PR1 in human colon biopsies

Zhang, Hongwei, Ciccimaro, Eugene, Zalaznick, Jacob, Sleczka, Bogdan G, Menard, Laurence, Olah, Timothy V, Shipkova, Petia

Journal:

Year:

2020

File:

PDF, 1007 KB

2020

6

Antibody Drug-Target Engagement Measurement in Tissue Using Quantitative Affinity Extraction Liquid Chromatography–Mass Spectrometry: Method Development and Qualification

Ciccimaro, Eugene, Zhu, Yongxin, Ostanin, Dmitry, Suchard, Suzanne, MacGuire, Jamus, Xiao, Qing, Dongre, Ashok, Chimalakonda, Anjaneya, Olah, Timothy, Shipkova, Petia

Journal:

Analytical Chemistry

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

7

Strategy to Improve the Quantitative LC-MS Analysis of Molecular Ions Resistant to Gas-Phase Collision Induced Dissociation: Application to Disulfide-Rich Cyclic Peptides

Ciccimaro, Eugene, Ranasinghe, Asoka, D’Arienzo, Celia, Xu, Carrie, Onorato, Joelle, Drexler, Dieter M., Josephs, Jonathan L., Poss, Michael, Olah, Timothy

Journal:

Analytical Chemistry

Year:

2014

Language:

english

File:

PDF, 731 KB

english, 2014

8

Exploitation of the Ornithine Effect Enhances Characterization of Stapled and Cyclic Peptides

Crittenden, Christopher M., Parker, W. Ryan, Jenner, Zachary B., Bruns, Kerry A., Akin, Lucas D., McGee, William M., Ciccimaro, Eugene, Brodbelt, Jennifer S.

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2016

Language:

english

File:

PDF, 754 KB

english, 2016

9

Analysis of phosphorylation sites on focal adhesion kinase using nanospray liquid chromatography/multiple reaction monitoring mass spectrometry

Eugene Ciccimaro, John Hevko, Ian A. Blair

Journal:

Rapid Communications in Mass Spectrometry

Year:

2006

Language:

english

File:

PDF, 792 KB

english, 2006

10

Stable-isotope dilution LC–MS for quantitative biomarker analysis

Ciccimaro, Eugene, Blair, Ian A

Journal:

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

11

Liquid chromatography/mass spectrometry of pre-ionized Girard P derivatives for quantifying estrone and its metabolites in serum from postmenopausal women

Kannan Rangiah, Sumit J. Shah, Anil Vachani, Eugene Ciccimaro, Ian A. Blair

Journal:

Rapid Communications in Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 1.63 MB

english, 2011

12

The Post-Synaptic Density of Human Postmortem Brain Tissues: An Experimental Study Paradigm for Neuropsychiatric Illnesses

Hahn, Chang-Gyu, Banerjee, Anamika, MacDonald, Matthew L., Cho, Dan-Sung, Kamins, Joshua, Nie, Zhiping, Borgmann-Winter, Karin E., Grosser, Tilo, Pizarro, Angel, Ciccimaro, Eugene, Arnold, Steven E.,

Journal:

Year:

2009

Language:

english

File:

PDF, 493 KB

english, 2009

13

Determination of Real Time In Vivo Drug Receptor Occupancy for a Covalent Binding Drug As a Clinical Pharmacodynamic (PD) Biomarker by Immunocapture-LC-MS/MS

Zheng, Naiyu, Catlett, Ian M., Taylor, Kristin, Gu, Huidong, Pattoli, Mark A., Neely, Robert J., Li, Wenying, Allentoff, Alban, Yuan, Xiling, Ciccimaro, Eugene, Yao, Ming, Warrack, Bethanne M., Burke,

Journal:

Analytical Chemistry

Year:

2019

Language:

english

File:

PDF, 510 KB

english, 2019

14

Bioanalysis Young Investigator: Eugene Ciccimaro

Ciccimaro, Eugene, Blair, Ian A

Journal:

Year:

2012

Language:

english

File:

PDF, 708 KB

english, 2012

15

Analytical considerations for quantitative LC–MS strategies for measuring antibody drug–target engagement in tissues

Shipkova, Petia, Ciccimaro, Eugene, Olah, Timothy V

Journal:

Year:

2017

Language:

english

File:

PDF, 164 KB

english, 2017

16

Absolute Quantification of Phosphorylation on the Kinase Activation Loop of Cellular Focal Adhesion Kinase by Stable Isotope Dilution Liquid Chromatography/Mass Spectrometry

Ciccimaro, Eugene, Hanks, Steven K., Yu, Kenneth H., Blair, Ian A.

Journal:

Analytical Chemistry

Year:

2009

Language:

english

File:

PDF, 2.16 MB

english, 2009

17

Immunoaffinity LC–MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker

Zhang, Hongwei, Gu, Huidong, Shipkova, Petia, Ciccimaro, Eugene, Sun, Huadong, Zhao, Qihong, Olah, Timothy V

Journal:

Year:

2017

Language:

english

File:

PDF, 1.28 MB

english, 2017

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